Improving Public Access to Aggregate Content of ClinicalTrials.gov

Note to Users

Effective September 15, 2026, an AACT account will be required to access and download AACT data. Account registration will enable CTTI to better measure AACT utilization, assess its value and impact, and prioritize future updates that enhance the resource for users.

What is AACT?

AACT is a publicly available relational database that contains all information (protocol and result data elements) about every study registered in ClinicalTrials.gov. Content is downloaded from ClinicalTrials.gov daily and loaded into AACT. The Clinical Trials Transformation Initiative (CTTI) enhanced AACT in October, 2016 to include the following features:

Database content refreshed daily
Database directly accessible in the cloud
Static copies of the database available for download
Open source tools freely available (postgreSQL, Ruby on Rails, Tableau Public)
Source code available via Github

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